3D Printing of Oral Solid Dosage Forms
Innovative technology, whole new possibilities – three-dimensional (3D) printing enables new approaches, especially in the context of drug production. Also referred to as additive manufacturing, 3D printing targets two hot topics of the pharmaceutical industry: personalized medicine and on-demand production. In fact, there’s an emerging trend to step away from mass manufacturing in favor of more personalized solutions. The reason: A strong demand for improved treatment options meeting individual patient needs, especially regarding pediatric and geriatric patients. But there’s more: 3D printing can also be key to shorter drug development times by supplying clinical trial material during the early stages.
However, in order to leverage the full potential of this highly digitalized technology, specialized excipients are required – as well as the integration of smart applications for self optimization or automated formulation development.
Our product offering is supported by the Emprove® Program with comprehensive documentation to speed up your way to the market. Whenever applicable, our products are compliant with the major pharmacopeias.
Excellent Solubility Enhancement and Stabilization
Our Parteck® MXP range of polyvinyl alcohol polymers with high thermal stability is optimal for a variety of additive manufacturing processes, especially melt-based technologies such as advanced melt drop deposition.
Meglumine Two Grades, Many Applications
The organic base meglumine can be used as a counterion to form a salt with the API or as a functional excipient to enhance API solubility, improve API stability, and adjust pH value. Select your grade:
Plasticizers Facilitate Formulation
Plasticizers can be used to reduce processing temperature, facilitating formulations with thermolabile APIs.
Our range of plasticizers suitable for 3D printing technologies includes:
Related Product Resources
- Download: Formulation Handbook
In this formulation handbook, we have compiled information and formulation examples that can help you when developing your formulation.
- Brochure: Double Your Benefit with Meglumine
Applicable either as an advanced API intermediate or as a functional excipient.
- Article: Solid Formulation Development Using Melt-based 3D Printing Technologies
3D printing can overcome challenges during formulation development, with a focus on enhancing API bioavailability in solid dispersions. Find out how in this technical article.
In this webinar, you will learn about the latest advancements in melt-based 3D printing, application examples for the individual technologies, and a deep dive into MED® 3D printing technology for designing dedicated drug release profiles.
In this webinar, we will introduce a new concept for additive manufacturing of challenging oral dosage forms. Combining Aprecia's commercial-scale 3D printing platform with our latest solubility enhancement technology, we are envisioning new manufacturing opportunities for formulation developers.
Poor solubility is a key challenge in todays’ formulation development. Tune in to our webinar to discover how the Developability Classification System (DCS) and Meglumine can support you with these challenges and more.
Para seguir leyendo, inicie sesión o cree una cuenta.
¿No tiene una cuenta?