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S006

Ketanserin (+)-tartrate salt

Name: Ketanserin (+)-tartrate salt
Brand: SIGMA
Price: 96.6 USD

≥97%, 5-HT2 serotonin receptor antagonist, solid

Sinónimos:

3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione (+)-tartrate salt, R 41468 (+)-tartrate salt

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Tamaño de envase	Disponibilidad	Precio
10 mg	Comprobar disponibilidad del carrito	$96.60
50 mg	Envío estimado HOYdesdeMILWAUKEE	$308.00
250 mg	Envío estimado HOYdesdeMILWAUKEE	$1,110.00
500 mg	Envío estimado HOYdesdeMILWAUKEE	$1,840.00 $1,564.00

Acerca de este artículo

Fórmula empírica (notación de Hill):

C₂₂H₂₂FN₃O₃ · C₄H₆O₆

Número CAS:

83846-83-7

Peso molecular:

545.51

NACRES:

NA.77

PubChem Substance ID:

24278121

UNSPSC Code:

12352202

EC Number:

281-062-8

MDL number:

MFCD00084651

Assay:

≥97%

Form:

solid

Quality level:

100

$96.60

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Propiedades

Nombre del producto

Ketanserin (+)-tartrate salt, ≥97%, solid

Quality Level

100

assay

≥97%

form

solid

color

white

solubility

ethanol: 3 mg/mL, DMSO: 52 mg/mL (lit.)(lit.), 0.1 M HCl: 6 mg/mL (lit.)(lit.)

storage temp.

2-8°C

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O.Fc1ccc(cc1)C(=O)C2CCN(CC2)CCN3C(=O)Nc4ccccc4C3=O

InChI

1S/C22H22FN3O3.C4H6O6/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29;5-1(3(7)8)2(6)4(9)10/h1-8,16H,9-14H2,(H,24,29);1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1

InChI key

KMTLTEVOQLMYRS-LREBCSMRSA-N

Gene Information

human ... HTR2A(3356), HTR2B(3357), HTR2C(3358)

Descripción

Application

Ketanserin (+)-tartrate salt has been used:

as a 5HT2A antagonist in Krebs-Henseleit buffer solution
for hormonal treatment to study the effects of exogenous manipulation of different hormonal systems in interaction with parasite infection on client′s behavior
to study the behavioural changes of incision pain rats

Biochem/physiol Actions

Selective 5-HT₂ serotonin receptor antagonist.

Selective 5-HT₂ serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction.

Ketanserin stimulates collagen synthesis and is involved in wound healing.

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Este artículo	SML1236	C221	V2264
Sigma-Aldrich S006 Ketanserin (+)-tartrate salt	Sigma-Aldrich SML1236 (−)-Nicotine hydrogen tartrate salt	Sigma-Aldrich C221 Carboxy-PTIO potassium salt	Sigma-Aldrich V2264 Vinorelbine ditartrate salt hydrate
assay ≥97%	assay ≥98% (HPLC)	assay ≥98% (TLC)	assay ≥98% (HPLC)
form solid	form powder	form powder	form powder
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. 2-8°C	storage temp. room temp	storage temp. 2-8°C	storage temp. 2-8°C
solubility ethanol: 3 mg/mL, 0.1 M HCl: 6 mg/mL (lit.)(lit.), DMSO: 52 mg/mL (lit.)(lit.)	solubility H₂O: 20 mg/mL, clear	solubility H₂O: 100 mg/mL, DMSO: soluble (lit.)(lit.), methanol: soluble (lit.)(lit.)	solubility H₂O: 10 mg/mL
color white	color white to beige	color -	color off-white