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Key Documents

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L6543

Sigma-Aldrich

Lacto-N-neo-tetraose

synthetic, ≥85% (HPLC)

Sinónimos:

β-D-Gal-(1→4)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-D-Glc, LNnT

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About This Item

Fórmula empírica (notación de Hill):
C26H45NO21
Número de CAS:
13007-32-4
Peso molecular:
707.63
MDL number:
MFCD00467190
UNSPSC Code:
12352201
PubChem Substance ID:
24896438
NACRES:
NA.25

biological source

synthetic

assay

≥85% (HPLC)

form

powder

storage temp.

2-8°C

SMILES string

CC(=O)NC1C(O)C(OC2OC(CO)C(O)C(O)C2O)C(CO)OC1OC3C(O)C(CO)OC(OC(C(O)CO)C(O)C(O)C=O)C3O

InChI

1S/C26H45NO21/c1-7(33)27-13-17(39)22(47-25-19(41)18(40)15(37)10(4-30)43-25)12(6-32)45-24(13)48-23-16(38)11(5-31)44-26(20(23)42)46-21(9(35)3-29)14(36)8(34)2-28/h2,8-26,29-32,34-42H,3-6H2,1H3,(H,27,33)

InChI key

RBMYDHMFFAVMMM-UHFFFAOYSA-N

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Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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David A Sela et al.
The Journal of biological chemistry, 286(14), 11909-11918 (2011-02-04)
Lactating mothers secrete milk sialyloligosaccharides (MSOs) that function as anti-adhesives once provided to the neonate. Particular infant-associated commensals, such as Bifidobacterium longum subsp. infantis, consume neutral milk oligosaccharides, although their ability to utilize acidic oligosaccharides has not been assessed. Temporal
Julie Elisabeth Heggelund et al.
International journal of molecular sciences, 20(3) (2019-02-10)
Diarrhea caused by enterotoxigenic Escherichia coli (ETEC) is one of the leading causes of mortality in children under five years of age and is a great burden on developing countries. The major virulence factor of the bacterium is the heat-labile
Behrouz Farhadihosseinabadi et al.
Scientific reports, 10(1), 997-997 (2020-01-24)
Lacto-n-neotatraose (LNnT) oligosaccharide shows properties such as anti-inflammatory, type 2 immune response induction, induced angiogenesis, and anti-bacterial effects. Here, we hypothesized that the application of LnNT in the skin full-thickness wound can accelerate the healing process through its anti-inflammatory effect
Liana Steeghs et al.
Cellular microbiology, 8(2), 316-325 (2006-01-31)
Neisseria meningitidis lipopolysaccharide (LPS) has been identified as a major determinant of dendritic cell (DC) function. Here we report that one of a series of meningococcal mutants with defined truncations in the lacto-N-neotetraose outer core of the LPS exhibited unique
Mohammad H Bohari et al.
Scientific reports, 6, 39556-39556 (2016-12-22)
Glycosphingolipids are ubiquitous cell surface molecules undertaking fundamental cellular processes. Lacto-N-tetraose (LNT) and lacto-N-neotetraose (LNnT) are the representative core structures for lacto- and neolacto-series glycosphingolipids. These glycolipids are the carriers to the blood group antigen and human natural killer antigens
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