3010
Transcreener® ADP2 FP Assay
Sinónimos:
Transcreener assay
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| Tamaño de envase | SKU | Disponibilidad | Precio |
|---|---|---|---|
| 1000 assays | Disponible para enviar HOYdesdeMILWAUKEE | $908.00 | |
| 10000 assays | Comprobar disponibilidad del carrito | $5,020.00 |
Acerca de este artículo
NACRES:
NA.81
UNSPSC Code:
41122100
$908.00
Disponible para enviar HOYDetalles
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarleshipped in
dry ice
storage temp.
−20°C
General description
The Transcreener® HTS Assay platform overcomes the need for time-consuming, one-off assay development for individual members within a group transfer enzyme family by utilizing a single set of assay reagents that detect an invariant product. The generic nature of the Transcreener® HTS Assay platform eliminates delays involved in assay development for new HTS targets, and greatly simplifies compound and inhibitor profiling across multiple target families.
The Transcreener® ADP2 FP Assay is a far-red, competitive fluorescence polarization (FP) assay based on the detection of ADP and therefore is compatible with any enzyme class that produces ADP, including protein, lipid, and carbohydrate kinases, ATPases, DNA helicases, carboxylases and glutamine synthetase. The Transcreener® ADP2 Assay is a simple one step homogenous detection assay, and is extremely flexible with regard to ATP concentration (0.1 to 1,000 μM ATP). The assay provides excellent signal at low substrate conversion, with a Z′ = 0.7 and = 85 polarization shift (mP) at 10% ATP conversion using 1 μM ATP.
The Transcreener® ADP2 FP Assay was developed to follow the progress of any enzyme that produces ADP. The Transcreener® ADP Detection Mixture comprises an ADP Alexa633 Tracer bound to an ADP2 Antibody. The tracer is displaced by ADP, the invariant product generated during the enzyme reaction.The displaced tracer freely rotates leading to a decrease in fluorescence polarization. The assay uses a far red tracer to minimize interference from fluorescent compounds and light scattering.
View full Transcreener® product list
The Transcreener® ADP2 FP Assay is a far-red, competitive fluorescence polarization (FP) assay based on the detection of ADP and therefore is compatible with any enzyme class that produces ADP, including protein, lipid, and carbohydrate kinases, ATPases, DNA helicases, carboxylases and glutamine synthetase. The Transcreener® ADP2 Assay is a simple one step homogenous detection assay, and is extremely flexible with regard to ATP concentration (0.1 to 1,000 μM ATP). The assay provides excellent signal at low substrate conversion, with a Z′ = 0.7 and = 85 polarization shift (mP) at 10% ATP conversion using 1 μM ATP.
The Transcreener® ADP2 FP Assay was developed to follow the progress of any enzyme that produces ADP. The Transcreener® ADP Detection Mixture comprises an ADP Alexa633 Tracer bound to an ADP2 Antibody. The tracer is displaced by ADP, the invariant product generated during the enzyme reaction.The displaced tracer freely rotates leading to a decrease in fluorescence polarization. The assay uses a far red tracer to minimize interference from fluorescent compounds and light scattering.
View full Transcreener® product list
Physical form
Kit with buffered aqueous solutions
Preparation Note
3010-1K = 1,000 assay, 384-well
3010-10K = 10,000 assay, 384-well
3010-10K = 10,000 assay, 384-well
Legal Information
Transcreener is a registered trademark of BellBrook Labs
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Este artículo | |||
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| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
signalword
Warning
Clase de almacenamiento
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
target_organs
Respiratory Tract
hcodes
Hazard Classifications
Eye Irrit. 2 - STOT RE 2 Inhalation
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Protocolos
Jump dilution protocol to determine the residence time of a drug (or drug candidate) during its interaction with a kinase using a fluorescence polarization assay based on the detection of ADP.
Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| 151815-10X0.75ML | 04061838739575 |
| 151815-10X1ML | 04061838739582 |
| 1017660009 | 04022536024455 |
| 48940-U | 04061832401669 |
| 175870-5G | 04061837613425 |
| 175870-25G | 04061838752574 |
| 175870-10X0.8ML-N | 04061837613401 |
| 175978-50G | 04061838752628 |
| 175978-10G | 04061838752611 |
| 364940-25G | 04061831825633 |
| 364940-10G | 04061831825626 |
| 364940-50G | 04061837656811 |
| 1017890100 | 04022536025315 |
| 1017660010 | 04022536694108 |
| 1017890009 | 04022536025292 |
| 1017890010 | 04022536025308 |
| 151815-10X50G-N | 04061837648854 |
| 151815-10G-AMP | 04061837613098 |
| 151815-10X1G-NA | 04061833691939 |
| 151815-100G | 04061837648847 |
| 151815-10X100G-N | 04061833691922 |