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MilliporeSigma

301310

Sigma-Aldrich

2-Ethyl-2-thiopseudourea hydrobromide

98%

Sinónimos:

S-Ethylisothiourea hydrobromide

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About This Item

Fórmula lineal:
C2H5SC(=NH)NH2 · HBr
Número de CAS:
Peso molecular:
185.09
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:

assay

98%

form

powder or crystals

mp

88-90 °C (lit.)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Br.CCSC(N)=N

InChI

1S/C3H8N2S.BrH/c1-2-6-3(4)5;/h2H2,1H3,(H3,4,5);1H

InChI key

SWXXKWPYNMZFTE-UHFFFAOYSA-N

Application

Reagent used in the synthesis of pyrimidines.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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W K Alderton et al.
The Biochemical journal, 332 ( Pt 1), 195-201 (1998-05-13)
Nitric oxide synthases (NOS) have a bidomain structure comprised of an N-terminal oxygenase domain and a C-terminal reductase domain. The oxygenase domain binds haem, (6R)-5,6,7,8-tetrahydro-l-biopterin (tetrahydrobiopterin) and arginine, is the site where nitric oxide synthesis takes place and contains determinants
Mihoko N Nakashima et al.
Journal of pharmacological sciences, 91(1), 47-52 (2003-04-11)
The possible role of nitric oxide (NO) in anxiety following transient cerebral ischemia by a 10-min bilateral carotid occlusion was examined in mice. Two days after the ischemia, mice showed a significant decrease in time spent on the open arms
E Alhan et al.
The European journal of surgery = Acta chirurgica, 164(9), 697-702 (1998-09-05)
To investigate the effects of the constitutive nitric oxide (NO) synthase inhibitor NG-nitro-L-arginine methyl ester (L-Name) and the inducible NO synthase inhibitor amino ethyl-isothiourea (AE-ITU) on acute necrotising pancreatitis (ANP) in rats. Laboratory study. Medical school, Turkey. Morbidity, mortality, effects
T Muraki et al.
Japanese journal of pharmacology, 70(3), 269-271 (1996-03-01)
By dye leakage in mouse skin, we evaluated the inhibition of proinflammatory stimuli-induced plasma extravasation by a putative inhibitor of inducible nitric oxide synthase, S-ethylisothiourea. A low dose of S-ethylisothiourea (5 micrograms/kg) mimicked aminoguanidine in inhibiting the plasma extravasation elicited
R L Rairigh et al.
The Journal of clinical investigation, 101(1), 15-21 (1998-02-14)
Nitric oxide (NO) produced by NO synthase (NOS) modulates fetal pulmonary vascular tone and contributes to the fall in pulmonary vascular resistance (PVR) at birth. Although the inducible (type II) NOS isoform is present in human and rat fetal lungs

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