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05-590

Sigma-Aldrich

Anti-phospho-STAT6 (Tyr641) Antibody, clone 16E12

clone 16E12, Upstate®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

16E12, monoclonal

species reactivity

human, mouse, rat

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG1

NCBI accession no.

NM_003153

UniProt accession no.

P42226

shipped in

dry ice

target post-translational modification

phosphorylation (pTyr641)

Gene Information

human ... STAT6(6778)

Specificity

phosphorylated STAT6

Immunogen

Peptide corresponding to residues of human STAT6 (Tyr641); recognizes STAT6 phosphorylated on Tyrosine 641.

Application

Detect phospho-STAT6 (Tyr641) also known as signal transducer & activator of transcription 6 with Anti-phospho-STAT6 (Tyr641) Antibody, clone 16E12 (mouse monoclonal antibody), that has been demonstrated to work in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

Quality

routinely evaluated by immunoblot on RIPA lysates from IL4-stimulated HepG2 cells

Target description

100kDa

Linkage

Replaces: MAB3702

Physical form

100µg of lyophilized thiophilic and size exclusion chromatography purified mouse IgG1 from 1mL 2x PBS / 0.09 % Na-azide / PEG and Sucrose. Reconstitute with 100 µL H2O (15 min, RT) for a final concentration of 1 mg/mL. Store at -20°C.
Format: Purified
Thiophilic adsoption and size exclusion chromatography

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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I González-Alvaro et al.
Annals of the rheumatic diseases, 68(10), 1644-1650 (2008-10-30)
To study the effects of different disease-modifying antirheumatic drugs (DMARD) on different events mediated by IL-15-activated lymphocytes. Peripheral blood lymphocytes (PBL) were isolated from healthy donors and activated with IL-15 after exposure to different DMARD: leflunomide, cyclosporin A, methotrexate, mycophenolic
Ji Huang et al.
International journal of molecular medicine, 36(2), 493-500 (2015-06-18)
Cisplatin-induced ototoxicity limits its wide application in the treatment of cancer. A number of pro-inflammatory factors have been shown to be involved in cisplatin-induced ototoxicity. Trichostatin A (TSA) is an anti-inflammatory agent that has been shown to exert protective effects

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