Saltar al contenido
MilliporeSigma
Todas las fotos(1)

Documentos

284718

Sigma-Aldrich

(−)-Cotinine

98%

Sinónimos:

(S)-1-Methyl-5-(3-pyridyl)-2-pyrrolidinone, S(−)-1-Methyl-5-(3-pyridyl)-2-pyrrolidone

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C10H12N2O
Número de CAS:
486-56-6
Peso molecular:
176.22
Beilstein/REAXYS Number:
83099
EC Number:
207-634-9
MDL number:
MFCD00077696
UNSPSC Code:
12352103
PubChem Substance ID:
329753204

assay

98%

optical activity

[α]20/D −21°, c = 1 in ethanol

bp

250 °C/150 mmHg (lit.)

mp

40-42 °C (lit.)

SMILES string

CN1[C@@H](CCC1=O)c2cccnc2

InChI

1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/t9-/m0/s1

InChI key

UIKROCXWUNQSPJ-VIFPVBQESA-N

¿Está buscando productos similares? Visita Guía de comparación de productos

Biochem/physiol Actions

Major metabolite of nicotine in humans.

Replaced by

Referencia del producto
Descripción
Precios

C5923

(−)-Cotinine, ≥98%

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

230.0 °F - closed cup

flash_point_c

110 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

V Haufroid et al.
International archives of occupational and environmental health, 71(3), 162-168 (1998-05-20)
A minireview is presented concerning the use of cotinine as a tobacco-smoke exposure index. First, general considerations about methods for the determination of urinary cotinine are presented. Besides pure analytical aspects, this minireview considers major problems encountered in the establishment
Ines Moreno-Gonzalez et al.
Nature communications, 4, 1495-1495 (2013-02-21)
Several epidemiological studies have shown that cigarette smoking might alter the incidence of Alzheimer's disease. However, inconsistent results have been reported regarding the risk of Alzheimer's disease among smokers. Previous studies in experimental animal models have reported that administration of
Natalie S Shenker et al.
Epidemiology (Cambridge, Mass.), 24(5), 712-716 (2013-07-23)
Most biomarkers of exposure tend to have short half-lives. This includes cotinine, a metabolite of nicotine widely used to assess smoke exposure. Cotinine is thus unsuitable as a determinant of past exposure to cigarette smoke. We used bisulphite pyrosequencing of
R R Watts et al.
Environmental health perspectives, 84, 173-182 (1990-03-01)
A two-day technical workshop was convened November 10-11, 1986, to discuss analytical approaches for determining trace amounts of cotinine in human body fluids resulting from passive exposure to environmental tobacco smoke (ETS). The workshop, jointly sponsored by the U.S. Environmental
Cotinine as a biomarker of environmental tobacco smoke exposure.
N L Benowitz
Epidemiologic reviews, 18(2), 188-204 (1996-01-01)
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico