UBB
ubiquitin B
Sinónimos:
Especie:
Human UBB (7314), Mouse Ubb (22187), Rat Ubb (192255), Zebrafish ubb (550134), chicken UBB (396190), dog UBB (479513), domestic cat UBB (101091319), Horse UBB (100049794), cow UBB (281370), naked mole-rat Ubb (101702552)
ID UniProtKB:
ID del gen:
- Human(7314) Summary: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq, Jul 2008]
- Mouse(22187) ubiquitin B
- Rat(192255) ubiquitin B
- Zebrafish(550134) ubiquitin B
- chicken(396190) ubiquitin B
- dog(479513) ubiquitin B
- domestic cat(101091319) ubiquitin B
- Horse(100049794) ubiquitin B
- cow(281370) ubiquitin B
- naked mole-rat(101702552) ubiquitin B
- domestic guinea pig(100722422) ubiquitin B
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-fosfo-ubiquitina (Ser65), from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, guinea pig, hamster, horse, human, mouse, nonhuman primates, rat, sheep
Aplicación
immunocytochemistry
western blot
western blot
Anti-Ubiquitin (pan) Antibody, clone 2G7B8, clone 2G7B8, from mouse,
Reactividad de especies
human
Aplicación
western blot
Anti-Ubiquitin Lys63 Antibody, clone HWA4C4 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
ELISA
affinity binding assay
western blot
affinity binding assay
western blot
Anti-Ubiquitin Rabbit pAb, liquid, Calbiochem®,
Reactividad de especies
drosophila, e. coli, bovine, canine, chicken, frog, guinea pig, hamster, human, monkey, mouse, rabbit, rat, sheep, yeast
Aplicación
Anti-phospho-Ubiquitin Antibody (Ser65), Alexa Fluor™ 488 Conjugate, from rabbit, ALEXA FLUOR™ 488,
Reactividad de especies
bovine, guinea pig, hamster, horse, human, mouse, nonhuman primates, rat, sheep
Aplicación
immunocytochemistry