TXNRD1
thioredoxin reductase 1
Sinónimos:
GRIM-12, TR, TR1, TRXR1, TXNR
Especie:
Human TXNRD1 (7296), Mouse Txnrd1 (50493), Rat Txnrd1 (58819), Horse TXNRD1 (100067923), domestic cat TXNRD1 (101085222), domestic guinea pig Txnrd1 (100718723), Domestic Rabbit TXNRD1 (100356179), naked mole-rat Txnrd1 (101700382), dog TXNRD1 (474536), sheep TXNRD1 (101112970) ...Más
ID UniProtKB:
ID del gen:
- Human(7296) Summary: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(50493) thioredoxin reductase 1
- Rat(58819) thioredoxin reductase 1
- Horse(100067923) thioredoxin reductase 1
- domestic cat(101085222) thioredoxin reductase 1
- domestic guinea pig(100718723) thioredoxin reductase 1
- Domestic Rabbit(100356179) thioredoxin reductase 1
- naked mole-rat(101700382) thioredoxin reductase 1
- dog(474536) thioredoxin reductase 1
- sheep(101112970) thioredoxin reductase 1
- cow(282388) thioredoxin reductase 1
- chicken(418082) thioredoxin reductase 1
- Zebrafish(352924) thioredoxin reductase 1
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Activity Assay
Referencia del producto
Descripción
Especie
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-TXNRD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
western blot
Anti-TXNRD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-Thioredoxin reductase 1 (TXNRD1 ) Antibody, clone 7P1J4, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot
Anti-TXNRD1 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Proteins
Referencia del producto
Descripción
Especie
Thioredoxin Reductase from rat liver, buffered aqueous glycerol solution, ≥100 units/mg protein (Bradford),
Especie
rat