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MilliporeSigma

TP53

tumor protein p53

Sinónimos:
BCC7, LFS1, P53, TRP53
Especie:
Human TP53 (7157), Rat Tp53 (24842), Domestic Rabbit TP53 (100009292), domestic guinea pig Tp53 (100379269), sheep TP53 (443421), cow TP53 (281542), Zebrafish tp53 (30590), naked mole-rat Tp53 (101701769), dog TP53 (403869), chicken TP53 (396200) ...Más
ID UniProtKB:
P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809
ID del gen:
  • Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
  • Rat(24842) tumor protein p53
  • Domestic Rabbit(100009292) tumor protein p53
  • domestic guinea pig(100379269) tumor protein p53
  • sheep(443421) tumor protein p53
  • cow(281542) tumor protein p53
  • Zebrafish(30590) tumor protein p53
  • naked mole-rat(101701769) tumor protein p53
  • dog(403869) tumor protein p53
  • chicken(396200) tumor protein p53
  • Horse(100062044) tumor protein p53
  • domestic cat(493847) tumor protein p53

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ELISA

Referencia del producto
Descripción
Especie
RAB0500
Human p53 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Especie
human
RAB0910
Rat Tp53 / Cellular Tumor Antigen p53 ELISA Kit, ,
Especie
rat

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
MABE339
Anti-p53 (wild type) Antibody, clone PAb1620, clone Pab1620, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
453M-9
p53 (DO7) Mouse Monoclonal Antibody, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
SAB5702066
Anti-Acetyl-p53-K382 Antibody, clone 0, Rabbit Monoclonal, ,
Reactividad de especies
mouse
Aplicación
CBL404
Anti-p53 Antibody, aa 211-220, clone240, clone PAb240, Chemicon®, from mouse,
Reactividad de especies
bovine, chicken, hamster, human, monkey, mouse, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
OP43
Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1), liquid, clone DO-1, Calbiochem®,
Reactividad de especies
feline, human
Aplicación

Cell Lines

Referencia del producto
Descripción
Especie
CLLS1049
MCF10A CELLS TP53 (-/-), ,
Especie
human
CLLS1007
SW48 Cells TP53 -/-, ,
Especie
human
CLLS1127
DLD1 Cells TP53 -/-, ,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
PZ0115
CP-31398 dihydrochloride hydrate, ≥98% (HPLC),
Especie
mouse, rat, human

Proteins

Referencia del producto
Descripción
Especie
23-034-M
p53 Protein, 10 µg, Full length, recombinant human p53. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.,
Especie
14-865
p53-GST (recombinant protein), ,
Especie
P6249
p53 human, recombinant, expressed in E. coli, buffered aqueous glycerol solution,
Especie
human
P6374
p53 human, recombinant, expressed in baculovirus infected Sf21 cells,
Especie
human
SRP2108
p53 (1-81), mutant, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU123221
MISSION® esiRNA, targeting human TP53,
Especie
human