SPTBN2
spectrin, beta, non-erythrocytic 2
Sinónimos:
GTRAP41, SCA5, SCAR14
Especie:
Human SPTBN2 (6712), Mouse Sptbn2 (20743), Rat Sptbn2 (29211), sheep SPTBN2 (101106728), domestic guinea pig Sptbn2 (100731189), dog SPTBN2 (483706), Zebrafish sptbn2 (322068), cow SPTBN2 (100336865), naked mole-rat Sptbn2 (101714181), Domestic Rabbit SPTBN2 (100355265) ...Más
ID UniProtKB:
ID del gen:
- Human(6712) Summary: Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]
- Mouse(20743) spectrin beta, non-erythrocytic 2
- Rat(29211) spectrin, beta, non-erythrocytic 2
- sheep(101106728) spectrin, beta, non-erythrocytic 2
- domestic guinea pig(100731189) spectrin, beta, non-erythrocytic 2
- dog(483706) spectrin, beta, non-erythrocytic 2
- Zebrafish(322068) spectrin, beta, non-erythrocytic 2
- cow(100336865) spectrin, beta, non-erythrocytic 2
- naked mole-rat(101714181) spectrin, beta, non-erythrocytic 2
- Domestic Rabbit(100355265) spectrin, beta, non-erythrocytic 2
- domestic cat(101089045) spectrin, beta, non-erythrocytic 2
- cow(100336410) spectrin, beta, non-erythrocytic 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-SPTBN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-SPTBN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Monoclonal Anti-SPTBN2 antibody produced in mouse, clone 4D9, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
western blot
Anti-Spectrin antibody produced in rabbit, whole antiserum,
Reactividad de especies
human
Aplicación
western blot
esiRNA
Referencia del producto
Descripción
Especie