SLC6A4
solute carrier family 6 (neurotransmitter transporter), member 4
Sinónimos:
5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT
Especie:
Human SLC6A4 (6532), Mouse Slc6a4 (15567), Rat Slc6a4 (25553), domestic guinea pig Slc6a4 (100135619), naked mole-rat Slc6a4 (101705584), Domestic Rabbit SLC6A4 (100340600), Domestic Rabbit SLC6A4 (100351801), dog SLC6A4 (491184), domestic cat SLC6A4 (101091163), Horse SLC6A4 (100053721) ...Más
ID UniProtKB:
ID del gen:
- Human(6532) Summary: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
- Mouse(15567) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Rat(25553) solute carrier family 6 (neurotransmitter transporter), member 4
- domestic guinea pig(100135619) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- naked mole-rat(101705584) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Domestic Rabbit(100340600) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Domestic Rabbit(100351801) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- dog(491184) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- domestic cat(101091163) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Horse(100053721) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- cow(282365) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- chicken(404747) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
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Small Molecule - Antagonist
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Especie
Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Serotonin (5-HT) Transporter (602-622) Rabbit pAb, lyophilized, Calbiochem®,
Reactividad de especies
mouse, rat
Aplicación
Anti-SLC6A4/5HTT/SERT antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
western blot
Anti-Serotonin transporter Antibody, clone 5T7M2, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
western blot
western blot
Monoclonal Anti-SLC6A4 antibody produced in mouse, clone 2A9, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
Anti-SLC6A4 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
bovine, human, mouse, rat
Aplicación
ELISA
flow cytometry
immunofluorescence
flow cytometry
immunofluorescence
Small Molecule - Inhibitor
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Descripción
Especie
Fluoxetina hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Escitalopram Oxalate, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Citalopram Hydrobromide, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Small Molecule - Ligand
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Especie
esiRNA
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Especie