SET
SET nuclear oncogene
Sinónimos:
2PP2A, I2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA
Especie:
Human SET (6418), Mouse Set (56086), Rat Set (307947), fruit fly Set (41844), chicken SET (417210), dog SET (608952), domestic cat SET (101081583), cow SET (538444), sheep SET (101118680), domestic guinea pig Set (100715138)
ID UniProtKB:
ID del gen:
- Human(6418) Summary: The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- Mouse(56086) SET nuclear oncogene
- Rat(307947) SET nuclear oncogene
- fruit fly(41844) CG4299 gene product from transcript CG4299-RA
- chicken(417210) SET nuclear oncogene
- dog(608952) SET nuclear oncogene
- domestic cat(101081583) SET nuclear oncogene
- cow(538444) SET nuclear oncogene
- sheep(101118680) SET nuclear oncogene
- domestic guinea pig(100715138) SET nuclear oncogene
- naked mole-rat(101720656) SET nuclear oncogene
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-SET antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SET (I2PP2A) Antibody, N-term Antibody, clone 10E7, clone 10E7, from mouse,
Reactividad de especies
human, monkey, rat
Aplicación
western blot
Anti-SET, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-SET-beta, clone 3D10E2, clone 3D10E2, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-SET-alpha, clone 5F4D9, clone 5F4D9, from mouse,
Reactividad de especies
human
Aplicación
western blot
esiRNA
Referencia del producto
Descripción
Especie