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PTPRJ

protein tyrosine phosphatase, receptor type, J

Sinónimos:
CD148, DEP1, HPTPeta, R-PTP-ETA, SCC1
Especie:
ID UniProtKB:
ID del gen:
  • Human(5795) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(19271) protein tyrosine phosphatase, receptor type, J
  • Rat(29645) protein tyrosine phosphatase, receptor type, J
  • chicken(395330) protein tyrosine phosphatase, receptor type, J
  • Domestic Rabbit(100347798) protein tyrosine phosphatase, receptor type, J
  • domestic cat(101086598) protein tyrosine phosphatase, receptor type, J
  • dog(483617) protein tyrosine phosphatase, receptor type, J
  • Horse(100058689) protein tyrosine phosphatase, receptor type, J
  • cow(508150) protein tyrosine phosphatase, receptor type, J
  • sheep(101121292) protein tyrosine phosphatase, receptor type, J
  • domestic guinea pig(100729887) protein tyrosine phosphatase, receptor type, J
  • naked mole-rat(101726039) protein tyrosine phosphatase, receptor type, J

Custom & Knockdown Gene Products

ELISA

Número de producto
Descripción
Especie
Human DEP-1 ELISA, for serum, plasma and cell culture supernatants,
Especie
human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-CD148-APC antibody produced in mouse, clone MEM-CD148/05,
Reactividad de especies
Aplicación
flow cytometry
Anti-Protein-tyrosine phosphatase eta (CD148) Antibody, clone 8A-1, clone 8A-1, from hamster(Syrian),
Reactividad de especies
mouse
Aplicación
flow cytometry
immunohistochemistry

western blot
Anti-PTPRJ antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Monoclonal Anti-CD148 antibody produced in mouse, clone MEM-CD148/05, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
flow cytometry
Anti-CD148/DEP-1 Antibody, clone Ab1 (Azide Free), clone Ab 1, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
immunoprecipitation (IP)

inhibition assay

western blot

Proteins

Número de producto
Descripción
Especie
DEP1 Active human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Ptprj,
Especie
mouse
MISSION® esiRNA, targeting human PTPRJ,
Especie
human