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PRKD3

protein kinase D3

Sinónimos:
EPK2, PKC-NU, PKD3, PRKCN, nPKC-NU
Especie:
ID UniProtKB:
ID del gen:
  • Human(23683) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members. [provided by RefSeq, Jul 2008]
  • Mouse(75292) protein kinase D3
  • Rat(313834) protein kinase D3
  • cow(538447) protein kinase D3
  • Domestic Rabbit(100340383) protein kinase D3
  • sheep(101120649) protein kinase D3
  • naked mole-rat(101696445) protein kinase D3
  • domestic guinea pig(100712662) protein kinase D3
  • chicken(421478) protein kinase D3
  • Zebrafish(557337) protein kinase D3
  • domestic cat(101100883) protein kinase D3
  • dog(483036) protein kinase D3
  • Horse(100054187) protein kinase D3

Custom & Knockdown Gene Products

  • siRNA

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PRKD3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
UCN-01, ≥97% (HPLC), powder,
Especie
human
GSK690693, ≥98% (HPLC),
Especie
human

Proteins

Referencia del producto
Descripción
Especie
Protein Kinase Cν (PKCν) Active human, recombinant, expressed in E. coli, ≥75% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Prkd3,
Especie
mouse
MISSION® esiRNA, targeting human PRKD3,
Especie
human