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MilliporeSigma

PLAT

plasminogen activator, tissue

Sinónimos:
T-PA, TPA
Especie:
ID UniProtKB:
ID del gen:
  • Human(5327) Summary: This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(18791) plasminogen activator, tissue
  • Rat(25692) plasminogen activator, tissue
  • naked mole-rat(101713266) plasminogen activator, tissue
  • domestic guinea pig(100725281) plasminogen activator, tissue
  • cow(281407) plasminogen activator, tissue
  • sheep(101118332) plasminogen activator, tissue
  • chicken(426791) plasminogen activator, tissue
  • domestic cat(101100299) plasminogen activator, tissue
  • Horse(100050239) plasminogen activator, tissue
  • dog(482840) plasminogen activator, tissue
  • Zebrafish(100320028) plasminogen activator, tissue
  • Domestic Rabbit(100009556) plasminogen activator, tissue

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ELISA

Referencia del producto
Descripción
Especie
Human TPA ELISA, for serum, plasma and cell culture supernatants,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PLAT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-PLAT antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-Tissue Plasminogen Activator (Ab-1) Mouse mAb (GMA-043), liquid, clone GMA-043, Calbiochem®,
Reactividad de especies
human
Aplicación
ANTI-TPA (CENTER) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
flow cytometry
immunohistochemistry

western blot
Anti-tPA/PLAT antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
6-Aminohexanoic acid, ≥98.5% (NT),
Especie
human
Aminocaproic acid, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Aminocaproic acid, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Aminocaproic acid, European Pharmacopoeia (EP) Reference Standard,
Especie
human
6-Aminocaproic acid, SAJ special grade, ≥99.0%,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
Tissue plasminogen activator human, ,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Plat,
Especie
mouse
MISSION® esiRNA, targeting human PLAT,
Especie
human