NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
Sinónimos:
APAA, UCE
Especie:
Human NAGPA (51172), Mouse Nagpa (27426), Rat Nagpa (360476), sheep NAGPA (101104545), cow NAGPA (515935), domestic cat NAGPA (101091582), dog NAGPA (490019), chicken NAGPA (416395), naked mole-rat Nagpa (101704527), domestic guinea pig Nagpa (100723215)
ID UniProtKB:
ID del gen:
- Human(51172) Summary: Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as 'uncovering enzyme' or UCE, this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties and thereby produces the recognition marker. This reaction most likely occurs in the trans-Golgi network. This enzyme functions as a homotetramer of two disulfide-linked homodimers. In addition to having an N-terminal signal peptide, the protein's C-terminus contains multiple signals for trafficking it between lysosomes, the plasma membrane, and trans-Golgi network. [provided by RefSeq, Jul 2008]
- Mouse(27426) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- Rat(360476) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- sheep(101104545) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- cow(515935) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- domestic cat(101091582) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- dog(490019) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- chicken(416395) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- naked mole-rat(101704527) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- domestic guinea pig(100723215) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-NAGPA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
esiRNA
Referencia del producto
Descripción
Especie