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MilliporeSigma

LTB

lymphotoxin beta (TNF superfamily, member 3)

Sinónimos:
TNFC, TNFSF3, p33
Especie:
ID UniProtKB:
ID del gen:
  • Human(4050) Summary: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(16994) lymphotoxin B
  • Rat(361795) lymphotoxin beta (TNF superfamily, member 3)
  • domestic cat(101085208) lymphotoxin beta (TNF superfamily, member 3)
  • dog(481712) lymphotoxin beta (TNF superfamily, member 3)
  • sheep(101122820) lymphotoxin beta (TNF superfamily, member 3)
  • cow(529757) lymphotoxin beta (TNF superfamily, member 3)
  • naked mole-rat(101716941) lymphotoxin beta (TNF superfamily, member 3)
  • domestic guinea pig(100722556) lymphotoxin beta (TNF superfamily, member 3)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-LTB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-LTB antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, rabbit
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human LTB,
Especie
human
MISSION® esiRNA, targeting mouse Ltb,
Especie
mouse