LMNA
lamin A/C
Sinónimos:
CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1
Especie:
Human LMNA (4000), Mouse Lmna (16905), Rat Lmna (60374), domestic guinea pig Lmna (100735212), chicken LMNA (415464), sheep LMNA (101107924), cow LMNA (404144), domestic cat LMNA (101086199), Horse LMNA (100057663), dog LMNA (480124) ...Más
ID UniProtKB:
ID del gen:
- Human(4000) Summary: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
- Mouse(16905) lamin A
- Rat(60374) lamin A/C
- domestic guinea pig(100735212) lamin A/C
- chicken(415464) lamin A/C
- sheep(101107924) lamin A/C
- cow(404144) lamin A/C
- domestic cat(101086199) lamin A/C
- Horse(100057663) lamin A/C
- dog(480124) lamin A/C
- Zebrafish(195815) lamin A
- naked mole-rat(101704567) lamin A/C
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Progerin Antibody, clone 13A4, clone 13A4, Upstate®, from mouse,
Reactividad de especies
human
Aplicación
ELISA
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot
Anticuerpo anti-prelamina-A, clon PL-1C7, clone PL-1C7, from mouse,
Reactividad de especies
human, mouse
Aplicación
ELISA
flow cytometry
immunocytochemistry
western blot
flow cytometry
immunocytochemistry
western blot
Anticuerpo anti-prelamina-A, clon 7G11, clone 7G11, from rat,
Reactividad de especies
mouse
Aplicación
immunofluorescence
western blot
western blot
Anti-Progerin antibody, Mouse monoclonal, clone 13A4, purified from hybridoma cell culture,
Reactividad de especies
human
Aplicación
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Lamin A/C Antibody, clone 4C11, clone 4C11, from mouse,
Reactividad de especies
syrian hamster, human, monkey, mouse, rat
Aplicación
ChIP
immunofluorescence
immunoprecipitation (IP)
western blot
immunofluorescence
immunoprecipitation (IP)
western blot