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KCNQ1

potassium voltage-gated channel, KQT-like subfamily, member 1

Sinónimos:
ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, KVLQT1, Kv1.9, Kv7.1, LQT, LQT1, RWS, SQT2, WRS
Especie:
ID UniProtKB:
ID del gen:
  • Human(3784) Summary: This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(16535) potassium voltage-gated channel, subfamily Q, member 1
  • Rat(84020) potassium voltage-gated channel, KQT-like subfamily, member 1
  • chicken(423090) potassium voltage-gated channel, KQT-like subfamily, member 1
  • naked mole-rat(101725681) potassium voltage-gated channel, KQT-like subfamily, member 1
  • domestic guinea pig(100379230) potassium voltage-gated channel, subfamily Q, member 1
  • sheep(101119596) potassium voltage-gated channel, KQT-like subfamily, member 1
  • domestic cat(101092644) potassium voltage-gated channel, KQT-like subfamily, member 1
  • Horse(100034129) potassium voltage-gated channel, KQT-like subfamily, member 1
  • cow(784876) potassium voltage-gated channel, KQT-like subfamily, member 1
  • dog(483669) potassium voltage-gated channel, KQT-like subfamily, member 1
  • Zebrafish(557498) potassium voltage-gated channel, KQT-like subfamily, member 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Potassium Channel KvLQT1 Antibody, CT, Chemicon®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-KCNQ1, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot
Anti-KCNQ1 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry

western blot
Anti-KCNQ1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Kcnq1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Retigabine, ≥98% (HPLC),
Especie
human
Retigabine, analytical standard,
Especie
human
Guanidina hydrochloride, for molecular biology, ≥99%,
Especie
human
Guanidina hydrochloride, ≥98%,
Especie
human
Guanidina hydrochloride, ≥99% (titration), organic base and chaeotropic agent,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human KCNQ1,
Especie
human
MISSION® esiRNA, targeting mouse Kcnq1,
Especie
mouse