HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase
Sinónimos:
HL
Especie:
Human HMGCL (3155), Mouse Hmgcl (15356), Rat Hmgcl (79238), Zebrafish hmgcl (394190), naked mole-rat Hmgcl (101716848), domestic guinea pig Hmgcl (100713291), domestic cat HMGCL (101099569), cow HMGCL (317658), chicken HMGCL (396316), dog HMGCL (478187)
ID UniProtKB:
ID del gen:
- Human(3155) Summary: The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Mouse(15356) 3-hydroxy-3-methylglutaryl-Coenzyme A lyase
- Rat(79238) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
- Zebrafish(394190) 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)
- naked mole-rat(101716848) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
- domestic guinea pig(100713291) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
- domestic cat(101099569) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
- cow(317658) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
- chicken(396316) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
- dog(478187) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
- sheep(101119699) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-HMGCL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-HMGCL antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Small Molecule - Inhibitor
Referencia del producto
Descripción
Especie
esiRNA
Referencia del producto
Descripción
Especie