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HLA-DMA

major histocompatibility complex, class II, DM alpha

Sinónimos:
D6S222E, DMA, HLADM, RING6
Especie:
Human HLA-DMA (3108)
ID UniProtKB:
P28067, Q29639, Q29640
ID del gen:
  • Human(3108) Summary: HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq, Jul 2008]

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA017295
Anti-HLA-DMA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
HPA012750
Anti-HLA-DMA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
WH0003108M1
Monoclonal Anti-HLA-DMA antibody produced in mouse, clone 3F12-F11, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry
western blot
SAB1408586
Anti-HLA-DMA antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
western blot