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GRID2

glutamate receptor, ionotropic, delta 2

Sinónimos:
GluD2
Especie:
ID UniProtKB:
ID del gen:
  • Human(2895) Summary: Human glutamate receptor delta-2 (GRID2) is a relatively new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. GRID2 is a predicted 1,007 amino acid protein that shares 97% identity with the mouse homolog which is expressed selectively in cerebellar Purkinje cells. A point mutation in mouse GRID2, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This strongly suggests a role for GRID2 in neuronal apoptotic death. [provided by RefSeq, Jul 2008]
  • Mouse(14804) glutamate receptor, ionotropic, delta 2
  • Rat(79220) glutamate receptor, ionotropic, delta 2
  • Domestic Rabbit(100342468) glutamate receptor, ionotropic, delta 2
  • naked mole-rat(101702643) glutamate receptor, ionotropic, delta 2
  • cow(536367) glutamate receptor, ionotropic, delta 2
  • dog(487863) glutamate receptor, ionotropic, delta 2
  • chicken(422520) glutamate receptor, ionotropic, delta 2
  • Zebrafish(448841) glutamate receptor, ionotropic, delta 2
  • sheep(101117078) glutamate receptor, ionotropic, delta 2
  • domestic cat(101084622) glutamate receptor, ionotropic, delta 2
  • Horse(100053364) glutamate receptor, ionotropic, delta 2
  • domestic guinea pig(100735199) glutamate receptor, ionotropic, delta 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GRID2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Monoclonal Anti-GRID2 antibody produced in mouse, clone 1A1, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
Anti-GRID2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GRID2,
Especie
human
MISSION® esiRNA, targeting mouse Grid2,
Especie
mouse