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Merck

GLRX2

glutaredoxin 2

Sinónimos:
CGI-133, GRX2
Especie:
Human GLRX2 (51022), Mouse Glrx2 (69367), Rat Glrx2 (114022), sheep GLRX2 (100135692), domestic cat GLRX2 (101091421), dog GLRX2 (478956), naked mole-rat Glrx2 (101697695), domestic guinea pig Glrx2 (100714233), chicken GLRX2 (424357), Zebrafish glrx2 (436677)
ID UniProtKB:
Q9NS18, Q3LR69, Q7L1N7, Q96JC0, Q9Y3D4
ID del gen:
  • Human(51022) Summary: The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression. [provided by RefSeq, Aug 2011]
  • Mouse(69367) glutaredoxin 2 (thioltransferase)
  • Rat(114022) glutaredoxin 2
  • sheep(100135692) glutaredoxin 2
  • domestic cat(101091421) glutaredoxin 2
  • dog(478956) glutaredoxin 2
  • naked mole-rat(101697695) glutaredoxin 2
  • domestic guinea pig(100714233) glutaredoxin 2
  • chicken(424357) glutaredoxin 2
  • Zebrafish(436677) glutaredoxin 2
  • cow(513762) glutaredoxin 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
ABS2053
Anti-Glutaredoxin-2 (Grx2), from rabbit, purified by affinity chromatography,
Reactividad de especies
baboon, chimpanzee, human, monkey
Aplicación
immunohistochemistry
western blot
SAB1403229
Monoclonal Anti-GLRX2 antibody produced in mouse, clone 3E9, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
HPA057224
Anti-GLRX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
HPA023087
Anti-GLRX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
SAB1400531
Anti-GLRX2 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot

esiRNA

Referencia del producto
Descripción
Especie
EHU141551
MISSION® esiRNA, targeting human GLRX2,
Especie
human