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Merck

GLRB

glycine receptor, beta

Sinónimos:
HKPX2
Especie:
ID UniProtKB:
ID del gen:
  • Human(2743) Summary: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  • Mouse(14658) glycine receptor, beta subunit
  • Rat(25456) glycine receptor, beta
  • naked mole-rat(101709956) glycine receptor, beta
  • dog(475477) glycine receptor, beta
  • Horse(100061981) glycine receptor, beta
  • domestic cat(101088482) glycine receptor, beta
  • cow(281198) glycine receptor, beta
  • sheep(101109484) glycine receptor, beta
  • domestic guinea pig(100727431) glycine receptor, beta
  • chicken(422411) glycine receptor, beta

Custom & Knockdown Gene Products

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Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
Isoflurane, ,
Especie
human
Halothane, United States Pharmacopeia (USP) Reference Standard,
Especie
human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GLRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Glycine Receptor Antibody, Chemicon®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
immunoprecipitation (IP)
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GLRB,
Especie
human
MISSION® esiRNA, targeting mouse Glrb,
Especie
mouse