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MilliporeSigma

GABRD

gamma-aminobutyric acid (GABA) A receptor, delta

Sinónimos:
EIG10, EJM7, GEFSP5
Especie:
ID UniProtKB:
ID del gen:
  • Human(2563) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(14403) gamma-aminobutyric acid (GABA) A receptor, subunit delta
  • Rat(29689) gamma-aminobutyric acid (GABA) A receptor, delta
  • Zebrafish(571422) gamma-aminobutyric acid (GABA) A receptor, delta
  • chicken(770710) gamma-aminobutyric acid (GABA) A receptor, delta
  • cow(508711) gamma-aminobutyric acid (GABA) A receptor, delta
  • dog(489609) gamma-aminobutyric acid (GABA) A receptor, delta
  • sheep(101122539) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic cat(101087589) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic guinea pig(100735228) gamma-aminobutyric acid (GABA) A receptor, delta
  • naked mole-rat(101700143) gamma-aminobutyric acid (GABA) A receptor, delta

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Oxazepam, ,
Especie
human
Meprobamate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Meprobamate, analytical standard,
Especie
human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
Midazolam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Diazepam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Oxazepam solution, 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Alprazolam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Etomidate, >98% (HPLC), powder,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Flunitrazepam, ,
Especie
human
Clonazepam, powder,
Especie
human, rat
Ganaxolone, ≥98% (HPLC), solid,
Especie
human, mouse
Diazepam, ,
Especie
human, rat

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GABRD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-GABRD antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, human, mouse, rabbit
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GABRD,
Especie
human
MISSION® esiRNA, targeting mouse Gabrd,
Especie
mouse