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DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

Sinónimos:
DNMT3A2, M.HsaIIIA
Especie:
ID UniProtKB:
ID del gen:
  • Human(1788) Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(13435) DNA methyltransferase 3A
  • Rat(444984) DNA (cytosine-5-)-methyltransferase 3 alpha
  • sheep(100500776) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Domestic Rabbit(100344715) DNA (cytosine-5-)-methyltransferase 3 alpha
  • cow(359716) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic cat(100510798) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Horse(100055881) DNA (cytosine-5-)-methyltransferase 3 alpha
  • dog(482996) DNA (cytosine-5-)-methyltransferase 3 alpha
  • naked mole-rat(101718745) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic guinea pig(100721625) DNA (cytosine-5-)-methyltransferase 3 alpha
  • chicken(421991) DNA (cytosine-5-)-methyltransferase 3 alpha

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-DNMT3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry
Anti-DNMT3A antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
western blot
Anti-DNMT3A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
bovine, human, mouse, rat
Aplicación
ELISA
western blot
Anti-DNMT3A2 Antibody, from rabbit,
Reactividad de especies
human
Aplicación
ELISA
immunocytochemistry

western blot
Anti- DNMT3A antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
5-Aza-2′-deoxycytidine, ≥97%,
Especie
human
5-Azacytidine, Hybri-Max, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma,
Especie
human
Azacitidine, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Azacitidine, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
5-Azacytidine, ≥98% (HPLC),
Especie
human

Proteins

Referencia del producto
Descripción
Especie
DNMT3a Active human, recombinant, expressed in baculovirus infected insect cells,
Especie
human
DNMT3A/DNMT3L active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human DNMT3A,
Especie
human
MISSION® esiRNA, targeting mouse Dnmt3a,
Especie
mouse