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DIABLO

diablo, IAP-binding mitochondrial protein

Sinónimos:
DFNA64, SMAC
Especie:
ID UniProtKB:
ID del gen:
  • Human(56616) Summary: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
  • Mouse(66593) diablo homolog (Drosophila)
  • Rat(288753) diablo, IAP-binding mitochondrial protein
  • chicken(416860) diablo, IAP-binding mitochondrial protein
  • cow(493999) diablo, IAP-binding mitochondrial protein
  • domestic guinea pig(100724526) diablo, IAP-binding mitochondrial protein
  • naked mole-rat(101708166) diablo, IAP-binding mitochondrial protein
  • sheep(101121971) diablo, IAP-binding mitochondrial protein
  • dog(477463) diablo, IAP-binding mitochondrial protein

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ELISA

Referencia del producto
Descripción
Especie
Mouse Diablo / Diablo Homolog, Mitochondrial ELISA Kit, ,
Especie
mouse
Rat DIABLO / Diablo Homolog (Drosophila) ELISA Kit, ,
Especie
rat

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-DIABLO antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-SMAC antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Smac antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Monoclonal Anti-DIABLO antibody produced in mouse, clone 4F9, ascites fluid,
Reactividad de especies
human
Aplicación
ELISA
western blot
Anti-Smac/Diablo Antibody, Chemicon®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human DIABLO, RP11-512M8.5,
Especie
human
MISSION® esiRNA, targeting mouse Diablo,
Especie
mouse