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MilliporeSigma

CYP51A1

cytochrome P450, family 51, subfamily A, polypeptide 1

Sinónimos:
CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1
Especie:
Human CYP51A1 (1595), chicken CYP51A1 (420548), dog CYP51A1 (475225), cow CYP51A1 (505060)
ID UniProtKB:
Q16850, A4D1F8, B2RAI4, B4DJ55, O00770, O00772, Q16784, Q8N1A8
ID del gen:
  • Human(1595) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • chicken(420548) cytochrome P450, family 51, subfamily A, polypeptide 1
  • dog(475225) cytochrome P450, family 51, subfamily A, polypeptide 1
  • cow(505060) cytochrome P450, family 51, subfamily A, polypeptide 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
MABS1259
Anti-CYP51A1 Antibody, clone N6-P2H5*G8, clone N6-P2H5*G8, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
HPA041325
Anti-CYP51A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
HPA043508
Anti-CYP51A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
SAB2107501
Anti-CYP51A1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
dog, guinea pig, horse, human, rat
Aplicación
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
K1003
Ketoconazole, 99.0-101.0% (EP, titration),
Especie
mouse, human, rat
UC280
Ketoconazole, ,
Especie
mouse, human, rat

esiRNA

Referencia del producto
Descripción
Especie
EHU105301
MISSION® esiRNA, targeting human CYP51A1, LRRD1,
Especie
human