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MilliporeSigma

CYP19A1

cytochrome P450, family 19, subfamily A, polypeptide 1

Sinónimos:
ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
Especie:
ID UniProtKB:
ID del gen:
  • Human(1588) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(13075) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Rat(25147) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Goat(100861413) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Horse(100009712) cytochrome P450, family 19, subfamily A, polypeptide 1
  • dog(494003) cytochrome P450, family 17, subfamily A, polypeptide 1
  • chicken(414854) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Domestic Rabbit(100328545) cytochrome P450, family 19, subfamily A, polypeptide 1
  • cow(281740) cytochrome P450, family 19, subfamily A, polypeptide 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Cytochrome P450 19A1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-CYP19A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-Aromatase Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, canine, chimpanzee, human, pig, porcine, rhesus macaque
Aplicación
western blot
Anti-Aromatase (CYP19A1) Antibody, clone 5C5N7, Rabbit Monoclonal, ,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-Aromatase Antibody, clone 1D23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey
Aplicación
affinity binding assay
immunohistochemistry

western blot

Cell Lines

Referencia del producto
Descripción
Especie
CypExpress Aromatase, ,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Letrozole, ≥98% (HPLC),
Especie
human
Exemestane, ≥98% (HPLC),
Especie
human
Letrozole, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Formestane, solid,
Especie
human
Letrozole, United States Pharmacopeia (USP) Reference Standard,
Especie
human

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
DL-Aminoglutethimide, ,
Especie
human, rat

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Cyp19a1,
Especie
mouse
MISSION® esiRNA, targeting human CYP19A1,
Especie
human