CDK11A
cyclin-dependent kinase 11A
Sinónimos:
CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, PITSLRE, p58GTA
Especie:
Human CDK11A (728642), Horse CDK11A (100033941), dog CDK11A (489591), naked mole-rat Cdk11a (101714919)
ID UniProtKB:
ID del gen:
- Human(728642) Summary: This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L1, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L1, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions, which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L1 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Many transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of only two have been determined so far. [provided by RefSeq, Jul 2008]
- Horse(100033941) cyclin-dependent kinase 11A
- dog(489591) cyclin-dependent kinase 11A
- naked mole-rat(101714919) cyclin-dependent kinase 11A
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-CDK11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-CDK11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry