CCND2
cyclin D2
Sinónimos:
KIAK0002
Especie:
Human CCND2 (894), Mouse Ccnd2 (12444), Rat Ccnd2 (64033), domestic guinea pig Ccnd2 (100730596), naked mole-rat Ccnd2 (101721480), chicken CCND2 (374047), dog CCND2 (611782), cow CCND2 (615414), domestic cat CCND2 (101090950), sheep CCND2 (100147799)
ID UniProtKB:
ID del gen:
- Human(894) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. [provided by RefSeq, Oct 2008]
- Mouse(12444) cyclin D2
- Rat(64033) cyclin D2
- domestic guinea pig(100730596) cyclin D2
- naked mole-rat(101721480) cyclin D2
- chicken(374047) cyclin D2
- dog(611782) cyclin D2
- cow(615414) cyclin D2
- domestic cat(101090950) cyclin D2
- sheep(100147799) cyclin D2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CCND2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-CCND2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
immunofluorescence
proximity ligation assay
western blot
proximity ligation assay
western blot
Anti-CCND2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-CCND2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-Cyclin D2 (Phospho-THR280), affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
western blot