BCL2A1
BCL2-related protein A1
Sinónimos:
ACC-1, ACC-2, BCL2L5, BFL1, GRS, HBPA1
Especie:
Human BCL2A1 (597), Rat Bcl2a1 (170929), cow BCL2A1 (282151), chicken BCL2A1 (395673), dog BCL2A1 (488770), naked mole-rat Bcl2a1 (101702935), domestic cat BCL2A1 (768283), sheep BCL2A1 (101114560), domestic cat BCL2A1 (101086480), domestic guinea pig Bcl2a1 (100732983)
ID UniProtKB:
ID del gen:
- Human(597) Summary: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Rat(170929) BCL2-related protein A1
- cow(282151) BCL2-related protein A1
- chicken(395673) BCL2-related protein A1
- dog(488770) BCL2-related protein A1
- naked mole-rat(101702935) BCL2-related protein A1
- domestic cat(768283) BCL2-related protein A1
- sheep(101114560) BCL2-related protein A1
- domestic cat(101086480) BCL2-related protein A1
- domestic guinea pig(100732983) BCL2-related protein A1
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti BCL2 related protein A1 Antibody, clone 23GB4820, Rabbit Monoclonal, clone 23GB4820, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
western blot
western blot
Anti-BCL2A1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-BCL2A1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
bovine, canine, human, pig
Aplicación
ELISA
western blot
western blot
Anti-BCL2A1/BFL-1 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
camelidae, bat, bovine, chimpanzee, human
Aplicación
immunohistochemistry
western blot
western blot
Anti-BFL-1 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
esiRNA
Número de producto
Descripción
Especie