BCL2A1
BCL2-related protein A1
Sinónimos:
ACC-1, ACC-2, BCL2L5, BFL1, GRS, HBPA1
Especie:
Human BCL2A1 (597), Rat Bcl2a1 (170929), cow BCL2A1 (282151), chicken BCL2A1 (395673), dog BCL2A1 (488770), naked mole-rat Bcl2a1 (101702935), domestic cat BCL2A1 (768283), sheep BCL2A1 (101114560), domestic cat BCL2A1 (101086480), domestic guinea pig Bcl2a1 (100732983)
ID UniProtKB:
ID del gen:
- Human(597) Summary: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Rat(170929) BCL2-related protein A1
- cow(282151) BCL2-related protein A1
- chicken(395673) BCL2-related protein A1
- dog(488770) BCL2-related protein A1
- naked mole-rat(101702935) BCL2-related protein A1
- domestic cat(768283) BCL2-related protein A1
- sheep(101114560) BCL2-related protein A1
- domestic cat(101086480) BCL2-related protein A1
- domestic guinea pig(100732983) BCL2-related protein A1
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-BCL2A1/ BFL-1, serum, from rabbit,
Reactividad de especies
human
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-BFL-1 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-BCL2A1/BFL-1 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
camelidae, bat, bovine, chimpanzee, human
Aplicación
immunohistochemistry
western blot
western blot
Anti-BFL-1 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-BCL2A1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
esiRNA
Referencia del producto
Descripción
Especie