ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
Sinónimos:
ATP6N1, ATP6N1A, Stv1, VPP1, Vph1, a1
Especie:
Human ATP6V0A1 (535), Mouse Atp6v0a1 (11975), Rat Atp6v0a1 (29757), Horse ATP6V0A1 (100052802), domestic guinea pig Atp6v0a1 (100717816), cow ATP6V0A1 (286768), Zebrafish atp6v0a1 (100332691), naked mole-rat Atp6v0a1 (101718747), domestic cat ATP6V0A1 (101096367), sheep ATP6V0A1 (101123476) ...Más
ID UniProtKB:
ID del gen:
- Human(535) Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(11975) ATPase, H+ transporting, lysosomal V0 subunit A1
- Rat(29757) ATPase, H+ transporting, lysosomal V0 subunit A1
- Horse(100052802) ATPase, H+ transporting, lysosomal V0 subunit a1
- domestic guinea pig(100717816) ATPase, H+ transporting, lysosomal V0 subunit a1
- cow(286768) ATPase, H+ transporting, lysosomal V0 subunit a1
- Zebrafish(100332691) ATPase, H+ transporting, lysosomal V0 subunit a1
- naked mole-rat(101718747) ATPase, H+ transporting, lysosomal V0 subunit a1
- domestic cat(101096367) ATPase, H+ transporting, lysosomal V0 subunit a1
- sheep(101123476) ATPase, H+ transporting, lysosomal V0 subunit a1
- dog(607705) ATPase, H+ transporting, lysosomal V0 subunit a1
- chicken(395474) ATPase, H+ transporting, lysosomal V0 subunit a1
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ATP6V0A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-ATP6V0A1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot
Anti-ATP6V0A1, (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, human, mouse, pig, rat
Aplicación
immunohistochemistry
western blot
western blot