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MilliporeSigma

ASL

argininosuccinate lyase

Sinónimos:
ASAL
Especie:
ID UniProtKB:
ID del gen:
  • Human(435) Summary: This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(109900) argininosuccinate lyase
  • Rat(59085) argininosuccinate lyase
  • Zebrafish(393423) argininosuccinate lyase
  • fruit fly(40682) asterless
  • dog(479704) argininosuccinate lyase
  • Horse(100060801) argininosuccinate lyase
  • Goat(100860854) argininosuccinate lyase
  • cow(512771) argininosuccinate lyase
  • naked mole-rat(101709923) argininosuccinate lyase

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ASL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-ASL antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-ASL (AB1) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ASL,
Especie
human
MISSION® esiRNA, targeting mouse Asl,
Especie
mouse