ASL
argininosuccinate lyase
ASAL
Human ASL (435), Mouse Asl (109900), Rat Asl (59085), Zebrafish asl (393423), fruit fly asl (40682), dog ASL (479704), Horse ASL (100060801), Goat ASL (100860854), cow ASL (512771), naked mole-rat Asl (101709923)
- Human(435) Summary: This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(109900) argininosuccinate lyase
- Rat(59085) argininosuccinate lyase
- Zebrafish(393423) argininosuccinate lyase
- fruit fly(40682) asterless
- dog(479704) argininosuccinate lyase
- Horse(100060801) argininosuccinate lyase
- Goat(100860854) argininosuccinate lyase
- cow(512771) argininosuccinate lyase
- naked mole-rat(101709923) argininosuccinate lyase
Custom & Knockdown Gene Products
siRNA
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shRNA
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Custom Gene Products
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Antibodies
Anti-ASL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry
western blot
western blot
Anti-ASL antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
human
western blot
Anti-ASL (AB1) antibody produced in rabbit, affinity isolated antibody,
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
western blot