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MilliporeSigma

AGTR1

angiotensin II receptor, type 1

Sinónimos:
AG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
Especie:
ID UniProtKB:
ID del gen:
  • Human(185) Summary: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
  • naked mole-rat(101714068) angiotensin II receptor, type 1
  • Domestic Rabbit(100009164) angiotensin II receptor, type 1
  • domestic guinea pig(100192325) angiotensin II receptor, type 1
  • sheep(443107) angiotensin II receptor, type 1
  • dog(403836) angiotensin II receptor, type 1
  • chicken(396065) angiotensin II receptor, type 1
  • cow(281607) angiotensin II receptor, type 1
  • domestic cat(101082936) angiotensin II receptor, type 1

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
ProteoMass Angiotensin II MALDI-MS Standard, vial of 10 nmol,
Especie
human
[Val5]-Angiotensin II acetate salt hydrate, ≥95% (HPLC), powder,
Especie
mouse, human, rat
[Asn1, Val5]-Angiotensin II, ≥97% (HPLC),
Especie
mouse, human, rat

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Telmisartan, ≥98% (HPLC), solid,
Especie
human
Valsartan, ≥98% (HPLC),
Especie
human
Valsartan, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Losartan Potassium, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Telmisartan, United States Pharmacopeia (USP) Reference Standard,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-AT1 Receptor Antibody, Chemicon®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-AGTR1 Antibody, clone 1I12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, human, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry

western blot
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, human, mouse, rabbit, rat, sheep
Aplicación
western blot
Anti-AT1R/AGTR1 Antibody, clone 8W6G0, Rabbit Monoclonal, ,
Reactividad de especies
human
Aplicación
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Captopril, ≥98% (HPLC), powder,
Especie
human, rat
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
Especie
human, rat, mouse

Proteins

Referencia del producto
Descripción
Especie
ChemiSCREEN Human Angiotensin II Receptor, Type I Membrane Preparation, Human AT1 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human AGTR1,
Especie
human