AANAT
aralkylamine N-acetyltransferase
Sinónimos:
DSPS, SNAT
Especie:
Human AANAT (15), Mouse Aanat (11298), Rat Aanat (25120), chicken AANAT (396066), sheep AANAT (443531), domestic guinea pig Aanat (100724241), domestic cat AANAT (101098178), dog AANAT (483331), Goat AANAT (100860947), cow AANAT (281583)
ID UniProtKB:
ID del gen:
- Human(15) Summary: The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Mouse(11298) arylalkylamine N-acetyltransferase
- Rat(25120) aralkylamine N-acetyltransferase
- chicken(396066) aralkylamine N-acetyltransferase
- sheep(443531) aralkylamine N-acetyltransferase
- domestic guinea pig(100724241) aralkylamine N-acetyltransferase
- domestic cat(101098178) aralkylamine N-acetyltransferase
- dog(483331) aralkylamine N-acetyltransferase
- Goat(100860947) aralkylamine N-acetyltransferase
- cow(281583) arylalkylamine N-acetyltransferase
- naked mole-rat(101713893) aralkylamine N-acetyltransferase
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-AANAT Antibody, serum, Chemicon®,
Reactividad de especies
bovine, fish, human, rat, sheep
Aplicación
western blot
ANTI-AANAT (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-phospho-Serotonin N-Acetyltransferase (N-Terminal) (pThr29) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
rat
Aplicación
western blot
Anti-AANAT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-Serotonin N-Acetyltransferase (C-Terminal) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
mouse, rat
Aplicación
western blot