- Aflatoxin exposure in Nigerian children with severe acute malnutrition.
Aflatoxin exposure in Nigerian children with severe acute malnutrition.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association (2017-11-28)
Amy McMillan, Justin B Renaud, Kevin M N Burgess, Adebola E Orimadegun, Olusegun O Akinyinka, Stephen J Allen, J David Miller, Gregor Reid, Mark W Sumarah
PMID29175577
ABSTRACT
Aflatoxin exposure is an important public health concern in sub-Saharan Africa as well as parts of Latin America and Asia. In addition to hepatocellular carcinoma, chronic aflatoxin exposure is believed to play a role in childhood growth impairment. The most reliable biomarker of chronic aflatoxin exposure is the aflatoxin-albumin adduct, as measured by ELISA or isotope dilution mass spectrometry (IDMS). In this report, we have used high resolution LC-MS/MS with IDMS to quantitate AFB
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