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6S RNA Mimics B-Form DNA to Regulate Escherichia coli RNA Polymerase.

Molecular cell (2017-10-11)
James Chen, Karen M Wassarman, Shili Feng, Katherine Leon, Andrey Feklistov, Jared T Winkelman, Zongli Li, Thomas Walz, Elizabeth A Campbell, Seth A Darst
ABSTRACT

Noncoding RNAs (ncRNAs) regulate gene expression in all organisms. Bacterial 6S RNAs globally regulate transcription by binding RNA polymerase (RNAP) holoenzyme and competing with promoter DNA. Escherichia coli (Eco) 6S RNA interacts specifically with the housekeeping σ