- Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation.
Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation.
Science advances (2021-09-16)
Ana Tapia-Abellán, Diego Angosto-Bazarra, Cristina Alarcón-Vila, María C Baños, Iva Hafner-Bratkovič, Baldomero Oliva, Pablo Pelegrín
PMID34524838
ABSTRACT
[Figure: see text].
MATERIALS
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Caspase-1 Inhibitor IV, The Caspase-1 Inhibitor IV, also referenced under CAS 154674-81-4, controls the biological activity of Caspase-1. This small molecule/inhibitor is primarily used for Cancer applications.