PHL85752

Isoscopoletin

phyproof^® Reference Substance

• Synonym(s): 6-Hydroxy-7-methoxycoumarin, 7-Methoxyesculetin, Esculetin 7-methyl ether, Isoscopoletin
• Empirical Formula (Hill Notation): C₁₀H₈O₄
• CAS Number: 776-86-3
• Molecular Weight: 192.17
• Beilstein/REAXYS Number: 157280
• MDL number: MFCD00016976
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• assay: ≥90.0% (HPLC)
• form: powder
• manufacturer/tradename: PhytoLab
• SMILES string: COc1cc2OC(=O)C=Cc2cc1O
• InChI: 1S/C10H8O4/c1-13-9-5-8-6(4-7(9)11)2-3-10(12)14-8/h2-5,11H,1H3
• InChI key: SYTYLPHCLSSCOJ-UHFFFAOYSA-N

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Isoscopoletin is a coumarin that is produced in many plant species by the demethylation of scoparone. It inhibits proliferation of both control and multidrug resistant leukemia cell lines. It also inhibits proliferation of hepatitis B virus in cellular systems.

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3