SRP2094

Fos-related antigen 1 human

recombinant, expressed in insect cells, ≥70% (SDS-PAGE)

• Synonym(s): FRA, FRA1, fra-1
• UNSPSC Code: 12352202
• NACRES: NA.26

Properties

• biological source: human
• recombinant: expressed in insect cells
• assay: ≥70% (SDS-PAGE)
• form: frozen liquid
• mol wt: ~31.2 kDa
• packaging: pkg of 5 μg
• storage condition: avoid repeated freeze/thaw cycles
• concentration: 350 μg/mL
• color: colorless to clear
• NCBI accession no.: NM_005438
• UniProt accession no.: P15407
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... FOSL1(8061)

Description

Biochem/physiol Actions

The fos-related antigen 1 (Fra-1, or FosL1: Fos-like antigen 1) is a member of the Fos onco-protein family and a component of AP-1 transcription factor. Similar to other members of the family, Fra-1 contains a leucine zipper domain and a highly conserved C-terminal region. Transcription of Fra-1 gene is regulated by multiple cis-elements and 12-O-tetradecanoylphorbol-13-acetate (TPA). Fra-1 expression is associated with proliferation and invasiveness of breast cancer cells and other cancer cells.

Physical form

Clear and colorless frozen liquid solution

Preparation Note

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable