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Key Documents

SAB4300113

Sigma-Aldrich

Anti-phospho-FOXO4 (pSer197) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-AFX antibody produced in rabbit, Anti-AFX1 antibody produced in rabbit, Anti-MGC120490 antibody produced in rabbit, Anti-MLLT7 antibody produced in rabbit, Anti-forkhead box O4 antibody produced in rabbit

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About This Item

MDL number:
MFCD03791410
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~65 kDa

species reactivity

human, rat, mouse

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(A-A-SP-M-D)

NCBI accession no.

NP_001164402.1

UniProt accession no.

P98177

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer197)

Gene Information

human ... FOXO4(4303)

Immunogen

Peptide sequence around phosphorylation site of serine 197 (A-A-S(p)-M-D), according to the protein FOXO4.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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