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EHU007921

Sigma-Aldrich

MISSION® esiRNA

targeting human RPGRIP1L

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TTCCTCCAGCATCCTCTGTTAGCACACTAGTTTTAGCACCAAGACCTAAACCAAGACAACGTTTAACACCTGTAGATAAGAAGGTATCTTTCGTGGATATCATGCCACATCAGAGTGATGTTTCACAAGAAGGCAGTGTAGATGAGGTAAAAGAGAATACTGAGAAAATGCAGCAAGGAAAAGATGATGTGTCTTTACTATCTGAAGGTCAGCTTGCAGAACAAAGCTTGGCATCTTCTGAAGATGAAACAGAAATAACAGAGGACTTGGAACCAGAAGTTGAAGAGGACATGTCAGCTTCTGACAGTGATGACTGTATTATTCCAGGTCCTATCTCCAAGAATATCAAACAGCCATCAGAAAAAATTCGGATTGAGATCATAGCTCTAAGCCTTAATGATTCTCAAGTAACCATGGATGACACTATCCAACGGC

Ensembl | human accession no.

ENSG00000103494

NCBI accession no.

NM_015272

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... RPGRIP1L(23322) , RPGRIP1L(23322)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Yeon Ja Choi et al.
PLoS genetics, 15(1), e1007914-e1007914 (2019-01-29)
Cilia-related proteins are believed to be involved in a broad range of cellular processes. Retinitis pigmentosa GTPase regulator interacting protein 1-like (RPGRIP1L) is a ciliary protein required for ciliogenesis in many cell types, including epidermal keratinocytes. Here we report that
Jayne F Martin Carli et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(7), 3946-3956 (2018-02-22)
Genetic variants within the FTO (α-ketoglutarate-dependent dioxygenase) gene have been strongly associated with a modest increase in adiposity as a result of increased food intake. These risk alleles are associated with decreased expression of both FTO and neighboring RPGRIP1L (retinitis

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