MABN359

Anti-SLC22A3 Antibody, clone 4H6.1

clone 4H6.1, from mouse

• Synonym(s): Solute carrier family 22 member 3, Extraneuronal monoamine transporter, EMT, Organic cation transporter 3, SLC22A3
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.43

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: 4H6.1, monoclonal
• species reactivity: human
• technique(s): western blot: suitable
• isotype: IgG1κ
• NCBI accession no.: NP_068812
• UniProt accession no.: O75751
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: human ... SLC22A3(6581)

Description

General description

Solute carrier family 22 member 3 (UniProt O75751; also known as EMT, Extraneuronal monoamine transporterorganic cation transporter 3, Organic cation transporter 3) is encoded by the SLC22A3 (also known as EMTH, OCT3) gene (Gene ID 6581) in human. Solute carrier family 22 member 3 is a multi-transmembrane protein that mediates the outward transport and clearance of endogenous small organic cations as well as a wide array of drugs and environmental toxins. Known substrates for this transporter include histamine, serotonin, norepinephrine, dopamine and MPP+.

Immunogen

Epitope: C-terminal

GST-tagged recombinant protein corresponding to the C-terminal of human SLC22A3.

Application

Anti-SLC22A3 Antibody, clone 4H6.1, Cat. No. MABN359, is a highly specific mouse monoclonal antibody, that targets SLC22A3 and has been tested in Western Blotting.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Quality

Evaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected SLC22A3 in 10 µg of human brain tissue lysate.

Target description

~70 kDa observed. Due to glycosylation, the target band appears larger than the calculated molecular weight of 61.3 kDa

Linkage

Replaces: MABN1039

Physical form

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to lot specific datasheet.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable