MABD86

Anti-CD349/Frizzled 9 Antibody, clone W3C4

clone W3C4-hMSC, from mouse

• Synonym(s): CD349, Frizzled-9, Frizzled 9, FZ-9, FzE6, FzD3
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: W3C4-hMSC, monoclonal
• species reactivity: human
• technique(s): flow cytometry: suitable
• isotype: IgMκ
• NCBI accession no.: NP_003499
• UniProt accession no.: O00144
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... FZD9(8326)

Description

General description

CD349 is a member of the Frizzled family, known as Frizzled-9 (Fz9, FZD9, hFz9, or FzE6) which was originally described as FZD3. Ten frizzled member have been identified in humans. FZD9 is a seven transmembrane G-protein-coupled receptor (GPCR), a receptor for Wnt proteins. It is involved in the activation of Wnt/β-catenin pathway (canonic Wnt signaling). FZD9 is predominately expressed in fetal and adult brain, testis, eye, skeletal muscle and kidney and is also expressed on Mesenchymal stem cells, and neural precursor cells. Frizzled proteins play important roles in controlling cell fate, proliferation, migration, tissue architecture and organogenesis during embryonic development and in adult organisms. FZD9 is an important factor for nervous system development and is critical for hippocampal development.

Immunogen

Whole WERI-RB-1 cells

Application

Anti-CD349/Frizzled 9 Antibody, clone W3C4 is an antibody against CD349/Frizzled 9 for use in Flow Cytometry.

Research Category
Stem Cell Research

Stem Cell Research

Research Sub Category
Pluripotent & Early Differentiation

Developmental Signaling

Quality

Evaluated by Flow Cytometry on WERI-RB-1 cells Flow Cytometry Analysis: 4 µg/mL of this antibody detected CD349/Frizzled 9 on 1X10^5 WERI-RB-1 cells.

Target description

65 kDa calculated

Physical form

Format: Purified

Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
WERI-RB-1 cells

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable