506165
p53, His•Tag®, Human, Recombinant, E. coli
Synonym(s):
Tumor Protein p53
About This Item
assay
≥80% (SDS-PAGE)
Quality Level
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
foreign activity
Proteases, none detected
shipped in
wet ice
storage temp.
−70°C
General description
This product has been discontinued.
Recombinant, human, wild-type p53 fused at the N-terminus to a His•Tag sequence and expressed in E. coli. p53, a tumor suppressor, blocks transformation and inhibits tumor cell growth. Numerous mutations in the p53 gene have been characterized in human cancers. Loss or mutation of p53 function is highly correlated with tumorigenesis. The purified protein is useful in DNA binding assays and as a protein kinase substrate.
Biochem/physiol Actions
Packaging
Warning
Physical form
Reconstitution
Other Notes
Zhang, L., et al. 2000. Cancer Res.60, 3655.
Fields, S., and Jang, S.K. 1990. Science249, 1046.
Michalovitz, D., et al. 1990. Cell62, 671.
Raycroft, L., et al. 1990. Science249, 1049.
Finlay, C.A., et al. 1989. Cell57, 1083.
Legal Information
Storage Class
10-13 - German Storage Class 10 to 13
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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