487952

NOC-7

A nitric oxide (NO) donor similar to NOC-5 but with a much shorter half-life of NO release.

• Synonym(s): NOC-7, 3-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-propanamine
• Empirical Formula (Hill Notation): C₅H₁₄N₄O₂
• CAS Number: 146724-84-7
• Molecular Weight: 162.19
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• assay: ≥90% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic); protect from light
• color: white
• solubility: 0.1 M NaOH: soluble; water: soluble
• shipped in: ambient
• storage temp.: −20°C
• InChI: 1S/C5H14N4O2/c1-6-4-3-5-8(2)9(11)7-10/h6,11H,3-5H2,1-2H3
• InChI key: AXAGAUVQMYPYHM-UHFFFAOYSA-N

Description

General description

A nitric oxide (NO) donor similar to NOC-5 (Cat. No. 487950) but with a much shorter half-life of NO release. Half-life (t_½) in PBS, pH 7.4 is 10 minutes at 22°C. Useful as a short-acting nitrovasodilator. Relatively stable in alkaline solution (pH ≥10.0).

A nitric oxide (NO) donor similar to NOC-5 (Cat. No. 487950) but with a much shorter half-life of NO release. Useful as a short-acting nitrovasodilator. Half-life (t_½) of NO release = 10 min (PBS, pH 7.4, 22°C).

Biochem/physiol Actions

Cell permeable: no

Primary Target
A nitric oxide (NO) donor

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Irritant (B)

Reconstitution

Following reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O jut prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.

Other Notes

Zhang, P., et al. 1996. Circulation94, 2235.
Hrabie, J.A., et al. 1993. J. Org. Chem.58, 1472.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable