344277

Forskolin, 1,9-Dideoxy-, Coleus forskohlii - CAS 64657-18-7 - Calbiochem

• Synonym(s): Forskolin, 1,9-Dideoxy-, Coleus forskohlii - CAS 64657-18-7 - Calbiochem, 7β-Acetoxy-8,13-epoxy-6β-hydroxy-labd-14-en-11-one
• Empirical Formula (Hill Notation): C₂₂H₃₄O₅
• CAS Number: 64657-18-7
• Molecular Weight: 378.50
• UNSPSC Code: 12352200

Properties

• assay: ≥95% (NMR)
• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• solubility: DMSO: 5 mg/mL; ethanol: soluble
• shipped in: ambient
• storage temp.: 10-30°C
• InChI: 1S/C22H34O5/c1-8-20(5)12-14(24)16-21(6)11-9-10-19(3,4)17(21)15(25)18(26-13(2)23)22(16,7)27-20/h8,15-18,25H,1,9-12H2,2-7H3/t15-,16+,17-,18-,20-,21+,22-/m0/s1
• InChI key: ZKZMDXUDDJYAIB-SUCLLAFCSA-N

Description

General description

This product has been discontinued.

Natural product that does not stimulate adenylate cyclase. For use as a negative control (EC₅₀ >1 mM).

A naturally occurring analog of forskolin that does not stimulate adenylate cyclase (EC₅₀ >1000 µM).

Biochem/physiol Actions

Cell permeable: no

Primary Target
A negative control that does not stimulate adenylate cyclase

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Harmful (C)

Reconstitution

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 4 months at 4°C.

Other Notes

Roscetti, G., et al. 1994. Eur. J. Pharmacol. 269, 17.
White, G., et al. 1992. Brain Res.586, 157.
Tehrani, M.H. 1989. Synapse4, 126.
Seamon, K.B., et al. 1984. Proc. Natl. Acad. Sci. USA 81, 5081.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 10-13 - German Storage Class 10 to 13