720844

4-Piperidinopiperidine-1-carbonyl chloride

• Synonym(s): 1,4′-Bipiperidinyl-1′-carbonyl chloride, 1-Chlorocarbonyl-4-piperidinopiperidine, [1,4′-Bipiperidine]-1′-carbonyl chloride
• Empirical Formula (Hill Notation): C₁₁H₁₉ClN₂O
• CAS Number: 103816-19-9
• Molecular Weight: 230.73
• MDL number: MFCD08445612
• UNSPSC Code: 12352100
• PubChem Substance ID: 329763755
• NACRES: NA.22

Properties

• mp: 60-64 °C
• SMILES string: ClC(=O)N1CCC(CC1)N2CCCCC2
• InChI: 1S/C11H19ClN2O/c12-11(15)14-8-4-10(5-9-14)13-6-2-1-3-7-13/h10H,1-9H2
• InChI key: YDNSNQRKIINKPV-UHFFFAOYSA-N

Description

application

Reactant for synthesis of:

• Macrocyclic ureas as selective Chk1 inhibitors
• Etoposide prodrug for dual prodrug-enzyme antitumor therapy
• Phosphodiesterase 4 inhibitors
• Camptothecin analogs

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H314
• pcodes: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable